Release date: 2007-03-20
A groundbreaking development in drug delivery has been made by scientists at the University of California, Santa Barbara (UCSB). In collaboration with the StrataGent Life Sciences Institute in Los Gatos, California, they have developed a novel pulsed microinjection system that allows for the painless and bruise-free delivery of protein-based medications directly into the skin. This innovation could revolutionize the way millions of injections are administered worldwide.
Every year, approximately 12 billion syringes are used globally for various types of injections, including vaccines, insulin, and other protein drugs. Traditional injection methods often cause discomfort due to the deep penetration of needles, which can damage nerves and blood vessels, leading to pain and bruising. The new microinjection system aims to eliminate these issues entirely.
The system operates at high speeds—over 100 meters per second—and uses tiny nozzles ranging from 50 to 100 microns in diameter. Each injection delivers between 2 and 15 nanoliters of liquid medication, making it highly precise and efficient. Clinical tests have demonstrated that this needle-free method is effective in delivering drugs directly into the skin without causing the typical side effects associated with conventional injections.
Designed as a pre-filled, disposable syringe, the device can be used for subcutaneous, intramuscular, or intradermal injections. Its modular design allows for customization depending on the type of drug and the intended route of administration. According to Samir Mitragotri, a professor of chemical engineering at UCSB, the system ensures accurate delivery of medication into the epidermis, significantly reducing patient discomfort.
This breakthrough has the potential to replace current injection systems that often lead to pain and bruising. The research was published online on March 6 in the journal *Proceedings of the National Academy of Sciences*.
— Information from: Kexun
Amino acids are the basic units of proteins and are essential organic compounds in life. There are about 500 different amino acids in nature, but among the amino acids that make up the proteins of living organisms, 20 are standard amino acids, which are connected in different sequences to form proteinaceous proteins that perform various physiological functions in living organisms.
Amino acids can be divided into the following categories according to their location and function in proteins
1.Essential amino acids
9 amino acids that the body cannot synthesize by itself or the synthesis speed cannot meet the needs, and must be ingest through food, including lysine, tryptophan, phenylalanine, methionine, threonine, isoleucine, leucine, valine and histidine (infants also need histidine).2.Non-essential amino acids
The human body can synthesize by itself and does not need to obtain directly from food, including glutamic acid, aspartate, alanine, serine, glycine, proline, cysteine, etc.3.Conditional essential amino acids
Under specific conditions (such as disease, stress), the human body's synthetic ability is reduced, and additional supplements are needed, such as arginine, glutamine, etc.Amino acids are also widely used in the field of skin care, as skin care ingredients, they mainly have the following effects
1.Moisturizing
Some amino acids such as glycine, alanine, etc. have good hygroscopic properties, which can help the skin retain moisture and enhance its moisturizing ability.2.Repair
Such as arginine, glutamic acid, etc. participate in the repair and regeneration process of skin cells, promoting wound healing.3.Anti-aging
Certain amino acids have antioxidant effects that can help fight free radical damage and slow down skin aging.4.Cleansing
Amino acid surfactants, such as sodium lauryl sarcosine, are commonly used in cleansing products for sensitive skin due to their mild, non-irritating properties.Therefore, amino acids are not only essential for human health, but also play an important role in beauty and skin care products.
Amino Acids,Taurine,L-Tyrosine, Food additives
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