Release date: 2009-03-31
On March 30th, a team of Chinese researchers conducted a study focusing on the protection of the heart during prolonged ischemia and its impact on heart transplantation outcomes. The study involved 26 patients who experienced cardiac ischemia lasting more than six hours due to various clinical reasons, with an average duration of (401 ± 43) minutes. During the procedure, the hearts were quickly exposed, and both left and right chambers were decompressed to reduce pressure. A cold solution known as St. Thomas was infused through the aortic root at 4°C, with a volume of 500 ml. The heart's surface was also rinsed with ice-cold physiological saline to lower its temperature effectively. After removal, 2000 ml of 4°C UW solution was administered antegrade through the aortic root for preservation.
For patients with elevated pulmonary artery pressure, intraoperative administration of thioprostone and continuous inhaled nitric oxide were used to manage this condition. All 26 patients underwent orthotopic heart transplantation using a double-chamber vein anastomosis technique. The results showed that all patients survived post-surgery. Twenty-one patients experienced spontaneous re-start of the heart, while five required electrical defibrillation. One week after surgery, echocardiography confirmed that all patients had normal chamber sizes, normal pulmonary artery pressures, and normal left ventricular ejection fractions.
One patient required re-surgery due to an abnormal coronary artery opening, which eventually allowed successful weaning from cardiopulmonary bypass. Another patient remained on a ventilator due to heart failure and kidney dysfunction, requiring a tracheotomy and bedside hemodialysis. Two patients developed first-degree atrioventricular block, which resolved without specific treatment. One patient had a moderate pericardial effusion but did not require intervention.
The study concluded that even when the donor heart exceeded the standard storage time, satisfactory short-term outcomes could still be achieved if adequate myocardial protection was maintained throughout the process. However, the researchers emphasized that it is still preferable to keep the heart retention time within the safe limit whenever possible. This research highlights the importance of advanced preservation techniques and careful patient selection in extending the viability of donor hearts for transplantation. Meditech Medical Network
Chili powder is a spice blend made from dried, ground chili peppers, often combined with other herbs and spices. It typically includes varieties of chili peppers like cayenne, ancho, or chipotle, along with ingredients such as cumin, Garlic Powder, oregano, and paprika. This blend varies in heat intensity depending on the types of chilies used and can range from mild to very hot.
Chili powder is a versatile ingredient used in numerous cuisines worldwide, especially in Mexican, Tex-Mex, Indian, and Thai dishes. It adds depth, flavor, and a distinctive warmth to soups, stews, chili con carne, marinades, and a wide array of savory recipes.
Chilli powder is a red or reddish-yellow, oily and uniform powder, a mixture of red chillies, yellow chillies, chilli seeds and some chilli rods crushed finely, with the inherent spicy aroma of chilli, which stings and sneezes on the nose. Authentic should be pounded out with a stone mortar, or you can directly use dried chillies in the sun or roasted in a pot over a moderate fire and then pounded into powder.
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Chili Powder, Chili Ground, Red chili powder, Chaotian chili powder
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