Clinical application of Curculigo

Clinical application

1. Effects on sexual organs and sexual function

Studies have shown that: Curculigo can improve the response of the pituitary to injection of luteinizing hormone-releasing hormone (LRH) in ovariectomized rats; increase the response of the ovary to luteinizing hormone (LH) in plasma, and thus play a role in improving sexual function . With the administration of Curculigo decoction, the weight of the anterior pituitary, the weight of the ovary and the weight of the uterus were significantly increased, and the specific binding of the HCG/LH receptor was increased in the rats, but there was no effect on the level of luteinizing hormone (LH) in the plasma. Experiments showed that: Curculigo ethanol 10g/kg/d gavage rats 7 days after oestration, for 21 consecutive days, the weight of seminal vesicles in ovariectomized rats increased significantly, suggesting that there is androgen-like effect. 5. The water extract of Curculigo rambutani has the effect of excitatory function.

2. Effect on immune function

Experiments show that: Curculigo curb enhances the immune function. The intragastric administration of ethanol extract of Curculigo can increase the percentage of phagocytosis and phagocytic index of mouse peritoneal macrophages, and significantly increase the decrease of T lymphocytes in mice with immune function induced by cyclophosphamide. Does not increase the percentage of normal mouse T lymphocytes.

3. The role of the central nervous system

The Lycorine contained in Curculigo species has a significant prolongation of the latencies of conditioned reflexes in rats, allowing the positive conditioned reflexes to disappear and recover afterwards; it has a pronounced sedative effect on mice and prolongs the hypnotic time of pentobarbital, and Significant pain relief and antipyretic effects. Curcuma alcohol extract is injected intraperitoneally into normal mice to prolong the incubation period of clonic convulsions caused by tetracycline.


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