Today's hot spot: Shapu Aisi stock suspension gene therapy re-emergence

Visiting the company's headquarters: the stock has been suspended and the factory is still recruiting

A few days ago, the "Clove Doctor" public issue released "A year of 750 million brainwashing medicines, please let go of the Chinese elderly" article, pointing to Shapu Aisi eye drops with brainwashing advertising marketing misleading Elderly, delayed cataract treatment. The article spread rapidly on the Internet, dragging the "Sharp Aisi Eye Drops" into the whirlpool of public questioning, causing a nearly one-sided criticism.

Subsequently, some media reported that the cost of the product was only 1.45 yuan, but it was to sell a bottle of 43.5 yuan. In 2016, gross profit was as high as 94.49%.

OFweek医疗科技网今日热点:莎普爱思股票停牌 基因治疗再显神威

On the afternoon of December 6, the State Food and Drug Administration issued an urgent notice, in view of the fact that some doctors in the medical profession have produced benzyl lysine eye drops for Zhejiang Shapu Aisi Pharmaceutical Co., Ltd. (trade name: Shapu love) Questioning the efficacy of the solution, requesting the Zhejiang Food and Drug Administration to urge the enterprise to start the clinical effectiveness test as soon as possible and in accordance with the relevant provisions of the Drug Administration Law of the People's Republic of China and the consistency evaluation of the quality and efficacy of generic drugs. The evaluation results were reported to the Drug Evaluation Center of the State Food and Drug Administration.

On the morning of December 7, the Zhejiang Food and Drug Administration said that it would forward the notice of the State Food and Drug Administration to Shapu Aisi Company, and requested the company to immediately conduct self-inspection of advertisements and immediately correct it if it did not meet the requirements.

DNA verification personal identity takes only a few minutes

American Association for the Advancement of Science (AAAS) technology news sharing platform EurekAlert! A few days ago, the University of Columbia and the New York Gene Center staff developed an inexpensive DNA sequencer to match it with custom software to make real-time DNA verification a reality.

Researchers in the latest issue of eLife magazine said that the technology is widely used to identify victims in large-scale disasters and analyze the evidence collected at the crime scene. The most direct use is to identify the wrong mark or Contaminated cell line.

NEJM major breakthrough: gene therapy re-emerges, reducing the incidence of annual bleeding in patients with hemophilia B by 96%

For people with hemophilia, bleeding is quite a kind of thing that makes my life uncontrollable. Due to the innate lack of necessary clotting factors, the patient may bleed when he is slightly traumatized. He can only be careful and walk like a glass man to live on the eggshell.

OFweek医疗科技网今日热点:莎普爱思股票停牌 基因治疗再显神威

According to the different types of clotting factors, hemophilia is divided into hemophilia A (deficient factor FVIII) and hemophilia B (deficiency factor FIX), of which hemophilia A accounts for the majority, hemophilia B About 12%.

After the recent gratifying results of spinal muscular atrophy (SMA), the headline of the New England Journal of Medicine on December 7 brought good news to hemophilia patients: Gene therapy SPK-9001 The incidence of bleeding in patients with hemophilia B is reduced by 96%, and the infusion of clotting factor is reduced by 99%, making it the first hemophilia gene therapy to achieve long-term success in clinical trials!

"Science" is heavy: MSKCC re-sentences: Some cancer patients are born with genes that respond to immunotherapy!

Today, the world's top cancer research center, Timothy A., a clinical medical scientist at the Sloan-Kettering Cancer Center (MSKCC). The Chan team wrote in the top journal Science, which found that the extent to which cancer patients benefit from immunological checkpoint inhibitor treatment is related to the congenital genetic characteristics they inherited from their parents. More importantly, they found genes that affect the patient's response to immune checkpoint inhibitor treatment.

This finding is significant not only to help doctors determine which patients are more suitable for immunotherapy, but also to help patients who have difficulty benefiting from immunological checkpoint treatments find a more appropriate treatment.

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