How good is the Chinese medicine to be crushed?

AMD's concept of traditional Chinese medicine is now deepening in pharmaceutical production and research and development, many Chinese medicine practitioners such as those aspects of the clinics, pharmacies, health care and other traditional Chinese medicine for crushing requirements have become more sophisticated, the production of Chinese medicine research and development over Chen The manufacturers of micro-grinders, who need to use the crusher for material crushing, will be our potential customers, and many customers ask the question: How fine can your crusher do? How many? My usual reaction is: How much do you need to do, or how many do you need to do? Many customers' answers are: the finer the better. And the problem is here. The finer the better, the more vague the concept. It can even be said that users with such requirements are unclear and vague about the concept of fineness. In fact, the fineness of the material we crush depends on the type of material and the requirements for the product. . To put it simply: your product meets the requirements of 200 mesh. Do you need to achieve 800 mesh or finer? This is not only a problem of pulverizer selection, but also a problem of crushing costs, and then the method and technical requirements for powder testing.
Since we are talking about the Chinese medicine superfine pulverizer, let's talk about Chinese medicine as an example. In the Chinese Pharmacopoeia, 200 mesh is already very fine powder. If we do Chinese medicine to nanoscale, what problems will it have? Will Chinese medicine be modified? This is a very serious problem, and it requires a lot of research. If we are not sure about this issue, then let's not mention the finer the better. The concept we proposed is: low-speed grinding and ultra-fine grinding, that is, Chinese medicine can do cell breakage. After the plant cell wall or animal cell membrane is broken, the active ingredient is fully dissolved, which can effectively improve the dissolution rate, significantly improve the efficacy of the traditional Chinese medicine, fully absorb the body, reduce the use and consumption of the medicine, and reduce the use cost of the medicine, thereby significantly improving the economic benefit.
To what extent does the smashing fineness achieve cell breakage? At present, most Chinese medicine ultrafine pulverizer manufacturers believe that the fineness of pulverization reaches 300 mesh, which can basically achieve the ultra-destructive level of most traditional Chinese medicines.
The cell scale of Chinese medicinal materials (botanical and animal medicine) is generally around 10um-100um. After the ultrafine pulverization of the traditional Chinese medicine ultrafine pulverizer, the fine powder of traditional Chinese medicine can reach 300 mesh sieve (300 mesh sieve inner diameter is 47um) all pass, its particle size distribution is about 50% at 12-15um, the upper limit size is <47um It is twice as large as the upper limit size of 100 mesh 75um 95% and 150 mesh (90um) 100% of the fine powder of Chinese medicine prescribed by the Chinese Pharmacopoeia in 2000. The analysis proves that after the Chinese herbal medicine has achieved 300 mesh, the comprehensive cell breaking rate can reach more than 90%. Observed by electron microscopy, almost no intact cells can be seen, and only cell debris is seen. Chinese medicine has the following distinctive features after ultrafine pulverization of cell walls:
First, improve bioavailability. After ultra-fine pulverization and breaking, the contents of the cells can be directly contacted with the solvent, and the active ingredients can all enter the solvent and be absorbed by the human body. The onset time of the drug is significantly shortened, and the action time of the drug on the human body is shorter and the intensity of action is higher. .
Second, the full homogenization of the Chinese medicine compound smash. Many Chinese medicines are compound, and multiple varieties are compounded. The active ingredients can be fully and uniformly mixed, and the various ingredients are evenly absorbed by the human body, which can also enhance the effect of the medicine. Therefore, another very important function of the pulverizer is: mixing, mixing at the same time as pulverizing, and the mixing effect of the compound Chinese medicine mixed by the pulverizer is better than that of the mixer.
Third, improve the industrial extraction rate of active ingredients. After the ultrafine cells of Chinese medicine are broken, the cell dissolution resistance is reduced, so the extraction rate can be significantly improved.
4. After the cell is broken, the eggs in the medicinal material will also be killed, reducing the threat of pests to Chinese medicinal materials.
Through our explanation, I believe that many potential users will realize this. The ultra-fine crushing of traditional Chinese medicine should not simply pursue fineness. In the pursuit of high fineness, we must consider the factors of equipment cost, actual demand and crushing cost. . Practice has proved that: Hebei Benchen Technology's research and development Chinese medicine superfine pulverizer can easily achieve 300 mesh ultra-micro cell breaks for thousands of traditional Chinese medicine varieties, especially fibrous Chinese medicine. Then, is it necessary for our customers to pursue 1000 or even 3,000 mesh? (Our Chinese medicine superfine pulverizer Zui high pulverization fineness can be more than 3000 purposes). Some friends have reported that other manufacturers claim to be doing thousands of samples, and the test results are not as good as our 300-mesh samples. It is obvious that the fineness of the powder is distributed. Among them, the proportion of 10um, the proportion of 20um, the proportion of 50um, the proportion of 70 or 100um, which requires professional testing methods. For example, the high-end airflow type ultrafine pulverizer commonly used by Zui can classify materials, so the powder may be finer, but the jet mill has limitations on the pulverization of certain fibrous Chinese medicines and viscous oily high-sugar Chinese medicines. For example, Ganoderma lucidum superfine powder, Ganoderma lucidum spore powder, rehmannia, medlar, frankincense, myrrh, etc., these varieties of airflow superfine pulverizer is no way. Therefore, the choice of crusher mainly depends on the variety of products and crushing requirements. In the case of meeting the requirements of crushing fineness, it is necessary to minimize the loss, reduce the loss of active ingredients, reduce the cost of crushing, and also depends on the complexity of equipment operation, floor space, power consumption, manpower, efficiency, output, etc. !
Taking the Chinese medicine ultra-micro as the research and development direction, taking the Chinese medicine crushing as an example to explain the selection of the ultra-fine pulverizer, the above is simply a brief description of the ultra-fine pulverization of traditional Chinese medicine. There are many cases of practical use of ultra-fine pulverizers. Health products, cosmetics, chemical products, building materials, electronics, military, etc. may all use ultra-fine powder. There are many articles in this article that can make a bright future. In order to let customers truly feel the effect of superfine pulverization of traditional Chinese medicine, Benchen still continues to provide free sample micro-grinding test policy. We can provide free test for samples within 500g, and the pulverized samples are sent back to customers. Fineness, distribution, and effect are tested by the customer, without adulteration, without falsification, with real results, I hope more users and future customers and us to obtain, exchange views on superfine smashing, and jointly improve Chinese medicine to more High-end development, and benefit the society together!

Carbohydrazide CAS NO. 497-18-7

Carbohydrazide can act as an oxygen scavenger to prevent corrosion, especially in boiler feedwater systems, rocket propellant assemblies, color image and soap stabilizers, Antioxidant rubber, boiler water deoxidizers and metal passivators. Carbohydrazide can also be used as an anticorrosive agent. Organic synthesis of intermediates.

CAS No. 497-18-7 EINECS 207-837-2

Molecular Formula CH₆N₄O Molecular Weight 90.08

Attributes:

Carbohydrazide is a white crystalline powder or granule. The effective content of carbohydrazide is from 98.0 to 100.0%.

Specifications:

Packaging and storage:

Pack 25 kg or 50 kg with woven bags or fiber drums.

Store in a cool, dry, well-ventilated area away from incompatible materials. Please close the container when not in use.

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